Hyper-inflammation occurs in Covid-19 and is associated with worse outcomes
Successful host defence against a pathogen can involve resistance or tolerance, with implications for prioritising either antimicrobial or immunomodulatory therapeutic approaches. Hyper-inflammation occurs in Covid-19 and is associated with worse outcomes.
The efficacy of dexamethasone in preventing mortality in critical Covid-19 suggests that inflammation has a causal role in death.